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KMID : 0043319990220040380
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Archives of Pharmacal Research
1999 Volume.22 No. 4 p.380 ~ p.383
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Synthesis and In Vitro Cytotoxicity of 1-Azanthraquinone-3-Carboxamides
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Lee Hee-Soon
Lee Chang-Wook
Yang Sung-Il
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Abstract
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Five 1-azzanthraquinone-3-carboxamides were synthesized and evaluated in vitro cytotoxicity against four human cancer cell lines. The most active compound, 7b, exhibited cytotoxic activity comparable to doxorubicin.
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KEYWORD
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Drug resistance, Chemotherapy, Azaanthraquinone, Cytotoxic activity, Doxorubicin, Acridine-4-carboxamide
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